{
  "version": "1.0",
  "created": "2026-03-31T12:43:40.119056",
  "last_updated": "2026-04-03T12:20:49.222375",
  "oura": {
    "sleep": {
      "date": "2026-04-03",
      "hours": 6.8,
      "deep_min": 62,
      "rem_min": 114,
      "avg_hrv": 36,
      "resting_hr": 46,
      "bedtime": "00:00",
      "wake_time": "07:12"
    },
    "readiness": {
      "date": "2026-04-03",
      "score": 88
    },
    "heart_rate": null,
    "steps": {
      "date": "2026-04-03",
      "count": 1909,
      "active_calories": 171
    },
    "exercise": {
      "date": "2026-04-03",
      "sessions": [
        {
          "type": "Hiking",
          "time": "23:43",
          "duration_min": 16,
          "calories": 47.42329406738281,
          "intensity": "easy",
          "avg_hr": 93,
          "max_hr": 100,
          "zone_minutes": {
            "z1": 13.2,
            "z2": 2.8,
            "z3": 0.0,
            "z4": 0.0,
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          "training_load": 18.8
        },
        {
          "type": "Housework",
          "time": "08:29",
          "duration_min": 19,
          "calories": 115.1907730102539,
          "intensity": "easy"
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      ]
    },
    "hrv_trend": [
      {
        "date": "2026-04-03",
        "hrv": 36
      },
      {
        "date": "2026-04-02",
        "hrv": 27
      },
      {
        "date": "2026-04-01",
        "hrv": 26
      },
      {
        "date": "2026-03-31",
        "hrv": 37
      },
      {
        "date": "2026-03-30",
        "hrv": 31
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      {
        "date": "2026-03-29",
        "hrv": 29
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      {
        "date": "2026-03-28",
        "hrv": 31
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      {
        "date": "2026-03-26",
        "hrv": 40
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      {
        "date": "2026-03-25",
        "hrv": 29
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      {
        "date": "2026-03-24",
        "hrv": 37
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      {
        "date": "2026-03-23",
        "hrv": 29
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      {
        "date": "2026-03-22",
        "hrv": 23
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      {
        "date": "2026-03-21",
        "hrv": 35
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    "last_sync": "2026-04-03T12:20:49.216557",
    "exercise_feed": [
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        "date": "2026-04-03",
        "type": "Hiking",
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        "duration_min": 16,
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        "avg_hr": 93,
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        "training_load": 18.8
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        "date": "2026-04-03",
        "type": "Housework",
        "time": "08:29",
        "duration_min": 19,
        "calories": 115,
        "intensity": "easy"
      },
      {
        "date": "2026-04-02",
        "type": "Yardwork",
        "time": "18:53",
        "duration_min": 17,
        "calories": 90,
        "intensity": "easy",
        "avg_hr": 84,
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        "date": "2026-04-02",
        "type": "Hiking",
        "time": "11:44",
        "duration_min": 61,
        "calories": 349,
        "intensity": "easy",
        "avg_hr": 85,
        "max_hr": 110,
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          "z1": 50.0,
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        "training_load": 72.0
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        "date": "2026-04-02",
        "type": "Hiking",
        "time": "08:35",
        "duration_min": 18,
        "calories": 63,
        "intensity": "easy",
        "avg_hr": 105,
        "max_hr": 119,
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          "z1": 6.2,
          "z2": 8.4,
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        "training_load": 33.2
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        "date": "2026-04-01",
        "type": "Hockey",
        "time": "21:53",
        "duration_min": 88,
        "calories": 674,
        "intensity": "easy",
        "avg_hr": 108,
        "max_hr": 149,
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          "z1": 40.6,
          "z2": 16.7,
          "z3": 12.9,
          "z4": 17.3,
          "z5": 0.5
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        "training_load": 184.4
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      {
        "date": "2026-04-01",
        "type": "Hockey",
        "time": "17:25",
        "duration_min": 65,
        "calories": 621,
        "intensity": "easy",
        "avg_hr": 120,
        "max_hr": 142,
        "zone_minutes": {
          "z1": 15.0,
          "z2": 0.0,
          "z3": 27.5,
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        "training_load": 187.5
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      {
        "date": "2026-04-01",
        "type": "Hiking",
        "time": "12:48",
        "duration_min": 31,
        "calories": 184,
        "intensity": "easy",
        "avg_hr": 89,
        "max_hr": 100,
        "zone_minutes": {
          "z1": 29.8,
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        "training_load": 32.2
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      {
        "date": "2026-03-31",
        "type": "Hiking",
        "time": "13:46",
        "duration_min": 54,
        "calories": 277,
        "intensity": "easy",
        "avg_hr": 95,
        "max_hr": 105,
        "zone_minutes": {
          "z1": 38.9,
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        "training_load": 69.1
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      {
        "date": "2026-03-30",
        "type": "Hockey",
        "time": "17:45",
        "duration_min": 28,
        "calories": 137,
        "intensity": "easy",
        "avg_hr": 80,
        "max_hr": 103,
        "zone_minutes": {
          "z1": 27.5,
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        "training_load": 28.5
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      {
        "date": "2026-03-30",
        "type": "Hockey",
        "time": "17:22",
        "duration_min": 23,
        "calories": 104,
        "intensity": "easy",
        "avg_hr": 93,
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        "zone_minutes": {
          "z1": 20.9,
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        "training_load": 25.1
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      {
        "date": "2026-03-30",
        "type": "Hiking",
        "time": "08:24",
        "duration_min": 54,
        "calories": 277,
        "intensity": "easy",
        "avg_hr": 81,
        "max_hr": 97,
        "zone_minutes": {
          "z1": 54.0,
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        "training_load": 54.0
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      {
        "date": "2026-03-29",
        "type": "Cycling",
        "time": "11:05",
        "duration_min": 60,
        "calories": 503,
        "intensity": "easy",
        "avg_hr": 102,
        "max_hr": 143,
        "zone_minutes": {
          "z1": 42.3,
          "z2": 3.0,
          "z3": 3.9,
          "z4": 10.8,
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        "training_load": 103.2
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      {
        "date": "2026-03-29",
        "type": "Hiking",
        "time": "08:33",
        "duration_min": 59,
        "calories": 459,
        "intensity": "easy",
        "avg_hr": 93,
        "max_hr": 115,
        "zone_minutes": {
          "z1": 35.3,
          "z2": 23.7,
          "z3": 0.0,
          "z4": 0.0,
          "z5": 0.0
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        "training_load": 82.7
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      {
        "date": "2026-03-28",
        "type": "Housework",
        "time": "15:01",
        "duration_min": 35,
        "calories": 218,
        "intensity": "easy"
      },
      {
        "date": "2026-03-28",
        "type": "Hiking",
        "time": "10:02",
        "duration_min": 57,
        "calories": 432,
        "intensity": "easy",
        "avg_hr": 87,
        "max_hr": 114,
        "zone_minutes": {
          "z1": 41.2,
          "z2": 15.8,
          "z3": 0.0,
          "z4": 0.0,
          "z5": 0.0
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        "training_load": 72.8
      },
      {
        "date": "2026-03-25",
        "type": "Hiking",
        "time": "12:26",
        "duration_min": 74,
        "calories": 334,
        "intensity": null
      },
      {
        "date": "2026-03-25",
        "type": "Hiking",
        "time": "07:49",
        "duration_min": 18,
        "calories": 41,
        "intensity": null
      },
      {
        "date": "2026-03-24",
        "type": "Hiking",
        "time": "17:08",
        "duration_min": 64,
        "calories": 309,
        "intensity": null
      },
      {
        "date": "2026-03-24",
        "type": "Crosscountryskiing",
        "time": "09:08",
        "duration_min": 73,
        "calories": 551,
        "intensity": null
      },
      {
        "date": "2026-03-23",
        "type": "Hockey",
        "time": "19:36",
        "duration_min": 15,
        "calories": 60,
        "intensity": null
      },
      {
        "date": "2026-03-23",
        "type": "Hiking",
        "time": "10:44",
        "duration_min": 48,
        "calories": 250,
        "intensity": null
      },
      {
        "date": "2026-03-23",
        "type": "Crosscountryskiing",
        "time": "08:59",
        "duration_min": 105,
        "calories": 685,
        "intensity": null
      },
      {
        "date": "2026-03-22",
        "type": "Walking",
        "time": "23:04",
        "duration_min": 10,
        "calories": 37,
        "intensity": null
      },
      {
        "date": "2026-03-22",
        "type": "Hockey",
        "time": "19:09",
        "duration_min": 70,
        "calories": 598,
        "intensity": null
      },
      {
        "date": "2026-03-22",
        "type": "Cycling",
        "time": "17:59",
        "duration_min": 13,
        "calories": 70,
        "intensity": null
      },
      {
        "date": "2026-03-22",
        "type": "Hockey",
        "time": "15:05",
        "duration_min": 21,
        "calories": 83,
        "intensity": null
      },
      {
        "date": "2026-03-22",
        "type": "Hiking",
        "time": "12:21",
        "duration_min": 81,
        "calories": 422,
        "intensity": null
      },
      {
        "date": "2026-03-22",
        "type": "Housework",
        "time": "10:10",
        "duration_min": 26,
        "calories": 145,
        "intensity": null
      },
      {
        "date": "2026-03-21",
        "type": "Hiking",
        "time": "12:36",
        "duration_min": 16,
        "calories": 49,
        "intensity": null
      }
    ]
  },
  "blood": {
    "latest_test": "2026-03-24",
    "markers": {
      "LDL Cholesterol": {
        "value": 174.0,
        "unit": "mg/dL",
        "range": "0-100",
        "status": "critical",
        "trend": [
          135.0,
          143.0,
          148.0,
          174.0
        ],
        "date": "2026-03-24",
        "action": "Doctor \u2014 discuss statin or PCSK9. Lifestyle: zero saturated fat, 35g fiber/day, omega-3 3g/day"
      },
      "ApoB": {
        "value": 125.0,
        "unit": "mg/dL",
        "range": "0-119",
        "status": "critical",
        "trend": [
          108.0,
          121.0,
          125.0,
          134.0
        ],
        "date": "2026-03-24",
        "action": "Doctor \u2014 correlates with LDL. Key cardiovascular risk marker"
      },
      "Ferritin": {
        "value": 651.0,
        "unit": "ng/mL",
        "range": "20-380",
        "status": "critical",
        "trend": [
          755.0,
          689.0,
          675.0,
          570.0,
          651.0
        ],
        "date": "2026-03-24",
        "action": "Doctor \u2014 persistently elevated. Rule out hemochromatosis or inflammation"
      },
      "Glucose": {
        "value": 101.0,
        "unit": "mg/dL",
        "range": "65-99",
        "status": "at_risk",
        "trend": [
          85.0,
          101.0,
          72.0,
          101.0,
          101.0
        ],
        "date": "2026-03-24",
        "action": "Lifestyle \u2014 cut refined carbs, increase fiber, strength training"
      },
      "Total Cholesterol": {
        "value": 239.0,
        "unit": "mg/dL",
        "range": "125-200",
        "status": "at_risk",
        "trend": [
          257.0,
          231.0,
          194.0,
          209.0,
          239.0
        ],
        "date": "2026-03-24",
        "action": "Driven by LDL. Will improve with LDL intervention"
      },
      "Triglycerides": {
        "value": 127.0,
        "unit": "mg/dL",
        "range": "0-150",
        "status": "at_risk",
        "trend": [
          181.0,
          266.0,
          108.0,
          132.0,
          127.0
        ],
        "date": "2026-03-24",
        "action": "In range but diet-responsive. Zero alcohol + low sugar"
      },
      "HDL": {
        "value": 42.0,
        "unit": "mg/dL",
        "range": "40-200",
        "status": "at_risk",
        "trend": [
          39.0,
          39.0,
          39.0,
          37.0,
          42.0
        ],
        "date": "2026-03-24",
        "action": "Low end. Improve with exercise, omega-3, and weight loss"
      },
      "ALT": {
        "value": 37.0,
        "unit": "U/L",
        "range": "9-46",
        "status": "at_risk",
        "trend": [
          24.0,
          25.0,
          31.0,
          22.0,
          37.0
        ],
        "date": "2026-03-24",
        "action": "In range but highest ever. Liver \u2014 reduce alcohol, monitor"
      },
      "Cortisol": {
        "value": 14.2,
        "unit": "\u00b5g/dL",
        "range": "4-22",
        "status": "at_risk",
        "trend": [
          16.9,
          12.4,
          11.4,
          10.3,
          14.2
        ],
        "date": "2026-03-24",
        "action": "Stress trending up. Sleep, meditation, reduce overtraining"
      },
      "Testosterone": {
        "value": 394.8,
        "unit": "ng/dL",
        "range": "250-1100",
        "status": "at_risk",
        "trend": [
          328.0,
          322.0,
          501.0,
          288.0,
          394.8
        ],
        "date": "2026-03-24",
        "action": "Recovered from 288 low but still suboptimal. Continue zinc, ashwagandha, sleep optimization"
      },
      "Vitamin D": {
        "value": 27.0,
        "unit": "ng/mL",
        "range": "30-100",
        "status": "at_risk",
        "trend": [
          21.0,
          24.0,
          31.0,
          24.0,
          24.0,
          27.0
        ],
        "date": "2026-03-24",
        "action": "Still below optimal despite supplementation. Increased to 5000 IU"
      },
      "hsCRP": {
        "value": 1.2,
        "unit": "mg/L",
        "range": "0-3",
        "status": "optimal",
        "trend": [],
        "date": "2026-03-24",
        "action": "Inflammation low \u2014 good sign"
      },
      "Vitamin B12": {
        "value": 612.0,
        "unit": "pg/mL",
        "range": "200-1100",
        "status": "optimal",
        "trend": [],
        "date": "2026-03-24",
        "action": "Solid"
      },
      "HbA1c": {
        "value": 5.3,
        "unit": "%",
        "range": "3-5.7",
        "status": "optimal",
        "trend": [],
        "date": "2026-03-24",
        "action": "Not diabetic despite glucose spikes"
      },
      "Magnesium": {
        "value": 2.2,
        "unit": "mg/dL",
        "range": "1.5-2.5",
        "status": "optimal",
        "trend": [],
        "date": "2026-03-24",
        "action": "Adequate"
      },
      "TSH": {
        "value": 2.66,
        "unit": "\u00b5IU/L",
        "range": "0.5-4.59",
        "status": "optimal",
        "trend": [],
        "date": "2026-03-24",
        "action": "Thyroid normal"
      },
      "Potassium": {
        "value": 4.6,
        "unit": "mmol/L",
        "range": "3.5-5.3",
        "status": "optimal",
        "trend": [],
        "date": "2026-03-24",
        "action": "Good"
      },
      "Estradiol": {
        "value": 26.15,
        "unit": "pg/mL",
        "range": "7.6-42.6",
        "status": "optimal",
        "trend": [],
        "date": "2026-03-24",
        "action": "First time tested \u2014 normal"
      },
      "Progesterone": {
        "value": 0.38,
        "unit": "ng/mL",
        "range": "0-1.4",
        "status": "optimal",
        "trend": [],
        "date": "2026-03-24",
        "action": "First time tested \u2014 normal"
      }
    },
    "inner_age": 50.6,
    "test_history": [
      {
        "date": "2023-01-24",
        "source": "InsideTracker",
        "marker_count": 0,
        "inner_age": 49.7
      },
      {
        "date": "2023-06-28",
        "source": "InsideTracker",
        "marker_count": 0,
        "inner_age": 50.7
      },
      {
        "date": "2024-04-15",
        "source": "InsideTracker",
        "marker_count": 0,
        "inner_age": 52.9
      },
      {
        "date": "2025-02-17",
        "source": "InsideTracker",
        "marker_count": 0,
        "inner_age": 44.1
      },
      {
        "date": "2025-08-27",
        "source": "InsideTracker",
        "marker_count": 0,
        "inner_age": 56.6
      },
      {
        "date": "2026-03-24",
        "source": "InsideTracker Ultimate",
        "marker_count": 19,
        "inner_age": 50.6
      },
      {
        "date": "2026-03-24",
        "source": "InsideTracker",
        "marker_count": 0,
        "inner_age": 50.6
      }
    ],
    "last_sync": "2026-04-03T11:46:00.866560"
  },
  "genetics": {
    "source": "23andMe v4 (GSA chip)",
    "raw_file": "genome_Vasilios_Syrros_v4_Full_20260402081234.txt",
    "date_analyzed": "2026-04-02",
    "total_snps": 601782,
    "no_call_rate_pct": 1.18,
    "apoe_status": {
      "genotype": "e3/e3",
      "rs429358": "TT",
      "rs7412": "CC",
      "interpretation": "Average Alzheimer's and cardiovascular risk"
    },
    "high_significance": [
      {
        "rsid": "rs6025",
        "gene": "F5 (Factor V)",
        "genotype": "CC",
        "interpretation": "Homozygous CC genotype",
        "affects": "Blood clotting resistance to anticoagulant protein C"
      },
      {
        "rsid": "rs429358",
        "gene": "APOE",
        "genotype": "TT",
        "interpretation": "\u03b52/\u03b52 genotype (APOE2) - lowest Alzheimer's risk, lower LDL",
        "affects": "Cholesterol metabolism, Alzheimer's disease risk"
      },
      {
        "rsid": "rs7412",
        "gene": "APOE",
        "genotype": "CC",
        "interpretation": "\u03b53 or \u03b54 allele",
        "affects": "Cholesterol metabolism, Alzheimer's disease risk"
      },
      {
        "rsid": "rs7903146",
        "gene": "TCF7L2",
        "genotype": "CT",
        "interpretation": "~1.4x increased diabetes risk",
        "affects": "Type 2 diabetes risk (strongest known locus)"
      },
      {
        "rsid": "rs1800562",
        "gene": "HFE",
        "genotype": "GG",
        "interpretation": "Homozygous GG genotype",
        "affects": "Iron overload risk (hemochromatosis)"
      },
      {
        "rsid": "rs2187668",
        "gene": "HLA-DQ2.5",
        "genotype": "TT",
        "interpretation": "Homozygous TT genotype",
        "affects": "Celiac disease susceptibility"
      },
      {
        "rsid": "rs7454108",
        "gene": "HLA-DQ8",
        "genotype": "TT",
        "interpretation": "DQ8 homozygous, increased celiac risk",
        "affects": "Celiac disease susceptibility"
      }
    ],
    "moderate_significance": [
      {
        "rsid": "rs1801133",
        "gene": "MTHFR",
        "genotype": "AG",
        "interpretation": "Heterozygous genotype"
      },
      {
        "rsid": "rs1801282",
        "gene": "PPARG",
        "genotype": "CC",
        "interpretation": "Normal insulin sensitivity"
      },
      {
        "rsid": "rs5186",
        "gene": "AGTR1",
        "genotype": "AC",
        "interpretation": "Intermediate risk"
      },
      {
        "rsid": "rs3798220",
        "gene": "LPA",
        "genotype": "TT",
        "interpretation": "Homozygous TT genotype"
      },
      {
        "rsid": "rs10455872",
        "gene": "LPA",
        "genotype": "AA",
        "interpretation": "Homozygous AA genotype"
      },
      {
        "rsid": "rs5219",
        "gene": "KCNJ11",
        "genotype": "CC",
        "interpretation": "K allele, normal insulin secretion"
      },
      {
        "rsid": "rs13266634",
        "gene": "SLC30A8",
        "genotype": "CT",
        "interpretation": "Heterozygous genotype"
      },
      {
        "rsid": "rs10811661",
        "gene": "CDKN2A/B",
        "genotype": "CT",
        "interpretation": "Heterozygous genotype"
      },
      {
        "rsid": "rs9939609",
        "gene": "FTO",
        "genotype": "AT",
        "interpretation": "Intermediate obesity risk (~1.3x)"
      },
      {
        "rsid": "rs17782313",
        "gene": "MC4R",
        "genotype": "TT",
        "interpretation": "Homozygous TT genotype"
      },
      {
        "rsid": "rs4988235",
        "gene": "MCM6/LCT",
        "genotype": "GG",
        "interpretation": "Homozygous GG genotype"
      },
      {
        "rsid": "rs7041",
        "gene": "GC/VDBP",
        "genotype": "CC",
        "interpretation": "Homozygous CC genotype"
      },
      {
        "rsid": "rs4588",
        "gene": "GC/VDBP",
        "genotype": "GG",
        "interpretation": "Isoform 1f or 2"
      },
      {
        "rsid": "rs4680",
        "gene": "COMT",
        "genotype": "AG",
        "interpretation": "Val/Met, intermediate metabolism"
      },
      {
        "rsid": "rs1815739",
        "gene": "ACTN3",
        "genotype": "CT",
        "interpretation": "R/X, intermediate phenotype"
      },
      {
        "rsid": "rs8192678",
        "gene": "PPARGC1A",
        "genotype": "CC",
        "interpretation": "Gly/Gly, superior aerobic capacity and mitochondrial function"
      },
      {
        "rsid": "rs2802292",
        "gene": "FOXO3",
        "genotype": "GT",
        "interpretation": "Heterozygous genotype"
      },
      {
        "rsid": "rs1042522",
        "gene": "TP53",
        "genotype": "CC",
        "interpretation": "Pro/Pro, potentially more efficient tumor suppression"
      },
      {
        "rsid": "rs1800566",
        "gene": "NQO1",
        "genotype": "GG",
        "interpretation": "Homozygous GG genotype"
      },
      {
        "rsid": "rs4880",
        "gene": "SOD2",
        "genotype": "AA",
        "interpretation": "Val/Val, reduced mitochondrial superoxide dismutase activity"
      },
      {
        "rsid": "rs6265",
        "gene": "BDNF",
        "genotype": "CC",
        "interpretation": "Homozygous CC genotype"
      },
      {
        "rsid": "rs1800497",
        "gene": "DRD2/ANKK1",
        "genotype": "GG",
        "interpretation": "Homozygous GG genotype"
      },
      {
        "rsid": "rs1229984",
        "gene": "ADH1B",
        "genotype": "CC",
        "interpretation": "Homozygous CC genotype"
      },
      {
        "rsid": "rs671",
        "gene": "ALDH2",
        "genotype": "GG",
        "interpretation": "Normal acetaldehyde metabolism"
      },
      {
        "rsid": "rs4149056",
        "gene": "SLCO1B1",
        "genotype": "TT",
        "interpretation": "Normal statin metabolism"
      }
    ],
    "categories": {
      "cardiovascular": [
        {
          "rsid": "rs1801133",
          "gene": "MTHFR",
          "genotype": "AG",
          "risk_allele": "T",
          "interpretation": "Heterozygous genotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs1801131",
          "gene": "MTHFR",
          "genotype": "TT",
          "risk_allele": "C",
          "interpretation": "Homozygous TT genotype",
          "significance": "low"
        },
        {
          "rsid": "rs6025",
          "gene": "F5 (Factor V)",
          "genotype": "CC",
          "risk_allele": "A",
          "interpretation": "Homozygous CC genotype",
          "significance": "high"
        },
        {
          "rsid": "rs429358",
          "gene": "APOE",
          "genotype": "TT",
          "risk_allele": "C (\u03b54)",
          "interpretation": "\u03b52/\u03b52 genotype (APOE2) - lowest Alzheimer's risk, lower LDL",
          "significance": "high"
        },
        {
          "rsid": "rs7412",
          "gene": "APOE",
          "genotype": "CC",
          "risk_allele": "T (\u03b52)",
          "interpretation": "\u03b53 or \u03b54 allele",
          "significance": "high"
        },
        {
          "rsid": "rs662",
          "gene": "PON1",
          "genotype": "CT",
          "risk_allele": "A",
          "interpretation": "Heterozygous genotype",
          "significance": "low"
        },
        {
          "rsid": "rs5186",
          "gene": "AGTR1",
          "genotype": "AC",
          "risk_allele": "C",
          "interpretation": "Intermediate risk",
          "significance": "moderate"
        },
        {
          "rsid": "rs1800796",
          "gene": "IL6",
          "genotype": "GG",
          "risk_allele": "C",
          "interpretation": "Higher IL-6 production, pro-inflammatory",
          "significance": "low"
        },
        {
          "rsid": "rs1800795",
          "gene": "IL6",
          "genotype": "GG",
          "risk_allele": "G",
          "interpretation": "Increased IL-6 levels",
          "significance": "low"
        },
        {
          "rsid": "rs1800629",
          "gene": "TNF",
          "genotype": "AG",
          "risk_allele": "A",
          "interpretation": "Intermediate TNF-alpha levels",
          "significance": "low"
        },
        {
          "rsid": "rs3798220",
          "gene": "LPA",
          "genotype": "TT",
          "risk_allele": "G",
          "interpretation": "Homozygous TT genotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs10455872",
          "gene": "LPA",
          "genotype": "AA",
          "risk_allele": "T",
          "interpretation": "Homozygous AA genotype",
          "significance": "moderate"
        }
      ],
      "metabolic": [
        {
          "rsid": "rs1801282",
          "gene": "PPARG",
          "genotype": "CC",
          "risk_allele": "G",
          "interpretation": "Normal insulin sensitivity",
          "significance": "moderate"
        },
        {
          "rsid": "rs7903146",
          "gene": "TCF7L2",
          "genotype": "CT",
          "risk_allele": "T",
          "interpretation": "~1.4x increased diabetes risk",
          "significance": "high"
        },
        {
          "rsid": "rs5219",
          "gene": "KCNJ11",
          "genotype": "CC",
          "risk_allele": "A",
          "interpretation": "K allele, normal insulin secretion",
          "significance": "moderate"
        },
        {
          "rsid": "rs13266634",
          "gene": "SLC30A8",
          "genotype": "CT",
          "risk_allele": "A",
          "interpretation": "Heterozygous genotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs4402960",
          "gene": "IGF2BP2",
          "genotype": "GT",
          "risk_allele": "T",
          "interpretation": "Heterozygous genotype",
          "significance": "low"
        },
        {
          "rsid": "rs10811661",
          "gene": "CDKN2A/B",
          "genotype": "CT",
          "risk_allele": "A",
          "interpretation": "Heterozygous genotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs9939609",
          "gene": "FTO",
          "genotype": "AT",
          "risk_allele": "A",
          "interpretation": "Intermediate obesity risk (~1.3x)",
          "significance": "moderate"
        },
        {
          "rsid": "rs17782313",
          "gene": "MC4R",
          "genotype": "TT",
          "risk_allele": "C",
          "interpretation": "Homozygous TT genotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs1042713",
          "gene": "ADRB2",
          "genotype": "AA",
          "risk_allele": "C",
          "interpretation": "Arg/Arg, higher metabolic rate and norepinephrine sensitivity",
          "significance": "low"
        },
        {
          "rsid": "rs1042714",
          "gene": "ADRB2",
          "genotype": "CC",
          "risk_allele": "G",
          "interpretation": "Homozygous CC genotype",
          "significance": "low"
        },
        {
          "rsid": "rs4994",
          "gene": "ADRB3",
          "genotype": "AA",
          "risk_allele": "C",
          "interpretation": "Homozygous AA genotype",
          "significance": "low"
        }
      ],
      "nutrient metabolism": [
        {
          "rsid": "rs4988235",
          "gene": "MCM6/LCT",
          "genotype": "GG",
          "risk_allele": "A (old nomenclature)",
          "interpretation": "Homozygous GG genotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs1801394",
          "gene": "MTRR",
          "genotype": "AG",
          "risk_allele": "A",
          "interpretation": "Intermediate enzyme activity",
          "significance": "low"
        },
        {
          "rsid": "rs1805087",
          "gene": "MTR",
          "genotype": "AA",
          "risk_allele": "A",
          "interpretation": "Potential B12/methionine metabolism issues",
          "significance": "low"
        },
        {
          "rsid": "rs602662",
          "gene": "FUT2",
          "genotype": "AA",
          "risk_allele": "A",
          "interpretation": "Non-secretor, reduced B12 absorption from food",
          "significance": "low"
        },
        {
          "rsid": "rs7041",
          "gene": "GC/VDBP",
          "genotype": "CC",
          "risk_allele": "A",
          "interpretation": "Homozygous CC genotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs4588",
          "gene": "GC/VDBP",
          "genotype": "GG",
          "risk_allele": "T",
          "interpretation": "Isoform 1f or 2",
          "significance": "moderate"
        },
        {
          "rsid": "rs1800562",
          "gene": "HFE",
          "genotype": "GG",
          "risk_allele": "A",
          "interpretation": "Homozygous GG genotype",
          "significance": "high"
        },
        {
          "rsid": "rs1799945",
          "gene": "HFE",
          "genotype": "CG",
          "risk_allele": "G",
          "interpretation": "Heterozygous carrier",
          "significance": "low"
        },
        {
          "rsid": "rs855791",
          "gene": "TMPRSS6",
          "genotype": "GG",
          "risk_allele": "T",
          "interpretation": "Homozygous GG genotype",
          "significance": "low"
        },
        {
          "rsid": "rs234706",
          "gene": "CBS",
          "genotype": "AG",
          "risk_allele": "T",
          "interpretation": "Heterozygous genotype",
          "significance": "low"
        },
        {
          "rsid": "rs1695",
          "gene": "GSTP1",
          "genotype": "AA",
          "risk_allele": "G",
          "interpretation": "Normal detox capacity",
          "significance": "low"
        },
        {
          "rsid": "rs1048943",
          "gene": "CYP1A1",
          "genotype": "TT",
          "risk_allele": "G",
          "interpretation": "Homozygous TT genotype",
          "significance": "low"
        }
      ],
      "mental_cognitive": [
        {
          "rsid": "rs4680",
          "gene": "COMT",
          "genotype": "AG",
          "risk_allele": "A (Met allele)",
          "interpretation": "Val/Met, intermediate metabolism",
          "significance": "moderate"
        },
        {
          "rsid": "rs6265",
          "gene": "BDNF",
          "genotype": "CC",
          "risk_allele": "A (Met)",
          "interpretation": "Homozygous CC genotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs53576",
          "gene": "OXTR",
          "genotype": "GG",
          "risk_allele": "A",
          "interpretation": "Lower oxytocin receptor expression, less empathy/social sensitivity",
          "significance": "low"
        },
        {
          "rsid": "rs4570625",
          "gene": "TPH2",
          "genotype": "GG",
          "risk_allele": "A",
          "interpretation": "Higher serotonin production",
          "significance": "low"
        },
        {
          "rsid": "rs6311",
          "gene": "HTR2A",
          "genotype": "TT",
          "risk_allele": "A",
          "interpretation": "Homozygous TT genotype",
          "significance": "low"
        },
        {
          "rsid": "rs1800497",
          "gene": "DRD2/ANKK1",
          "genotype": "GG",
          "risk_allele": "T (A1 allele)",
          "interpretation": "Homozygous GG genotype",
          "significance": "moderate"
        }
      ],
      "fitness": [
        {
          "rsid": "rs1815739",
          "gene": "ACTN3",
          "genotype": "CT",
          "risk_allele": "X",
          "interpretation": "R/X, intermediate phenotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs8192678",
          "gene": "PPARGC1A",
          "genotype": "CC",
          "risk_allele": "A",
          "interpretation": "Gly/Gly, superior aerobic capacity and mitochondrial function",
          "significance": "moderate"
        },
        {
          "rsid": "rs1800012",
          "gene": "COL1A1",
          "genotype": "AC",
          "risk_allele": "S",
          "interpretation": "Heterozygous genotype",
          "significance": "low"
        },
        {
          "rsid": "rs7136446",
          "gene": "COL5A1",
          "genotype": "CT",
          "risk_allele": "C",
          "interpretation": "Heterozygous genotype",
          "significance": "low"
        }
      ],
      "sleep_circadian": [
        {
          "rsid": "rs1801260",
          "gene": "CLOCK",
          "genotype": "AA",
          "risk_allele": "T",
          "interpretation": "Morning preference, earlier sleep/wake timing",
          "significance": "low"
        },
        {
          "rsid": "rs73598374",
          "gene": "ADA",
          "genotype": "CC",
          "risk_allele": "A",
          "interpretation": "Homozygous CC genotype",
          "significance": "low"
        }
      ],
      "longevity": [
        {
          "rsid": "rs2802292",
          "gene": "FOXO3",
          "genotype": "GT",
          "risk_allele": "A",
          "interpretation": "Heterozygous genotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs1042522",
          "gene": "TP53",
          "genotype": "CC",
          "risk_allele": "G",
          "interpretation": "Pro/Pro, potentially more efficient tumor suppression",
          "significance": "moderate"
        },
        {
          "rsid": "rs1800566",
          "gene": "NQO1",
          "genotype": "GG",
          "risk_allele": "T",
          "interpretation": "Homozygous GG genotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs4880",
          "gene": "SOD2",
          "genotype": "AA",
          "risk_allele": "A (Val)",
          "interpretation": "Val/Val, reduced mitochondrial superoxide dismutase activity",
          "significance": "moderate"
        }
      ],
      "drug metabolism": [
        {
          "rsid": "rs762551",
          "gene": "CYP1A2",
          "genotype": "AA",
          "risk_allele": "A",
          "interpretation": "Slow caffeine metabolizer, jitteriness/anxiety at normal doses",
          "significance": "low"
        },
        {
          "rsid": "rs1229984",
          "gene": "ADH1B",
          "genotype": "CC",
          "risk_allele": "A",
          "interpretation": "Homozygous CC genotype",
          "significance": "moderate"
        },
        {
          "rsid": "rs671",
          "gene": "ALDH2",
          "genotype": "GG",
          "risk_allele": "A",
          "interpretation": "Normal acetaldehyde metabolism",
          "significance": "moderate"
        },
        {
          "rsid": "rs4149056",
          "gene": "SLCO1B1",
          "genotype": "TT",
          "risk_allele": "C",
          "interpretation": "Normal statin metabolism",
          "significance": "moderate"
        }
      ],
      "immune": [
        {
          "rsid": "rs2187668",
          "gene": "HLA-DQ2.5",
          "genotype": "TT",
          "risk_allele": "A",
          "interpretation": "Homozygous TT genotype",
          "significance": "high"
        },
        {
          "rsid": "rs7454108",
          "gene": "HLA-DQ8",
          "genotype": "TT",
          "risk_allele": "T",
          "interpretation": "DQ8 homozygous, increased celiac risk",
          "significance": "high"
        }
      ]
    },
    "actionable_insights": [
      "APOE e3/e3: Average Alzheimer's risk - standard prevention strategies",
      "TCF7L2 CT: 1.4x T2D risk - prioritize blood sugar management, low glycemic diet",
      "FTO AT: Moderate obesity predisposition - appetite regulation important",
      "MTHFR C677T heterozygous: Supplement methylfolate, monitor homocysteine",
      "CYP1A2 AA: Slow caffeine metabolizer - limit to 1-2 cups before noon",
      "HLA-DQ8 positive: Celiac susceptibility - monitor gluten sensitivity",
      "MCM6/LCT GG: Lactose intolerance likely - consider dairy alternatives",
      "FUT2 AA: Non-secretor, reduced B12 absorption - supplement B12",
      "SOD2 AA (Val/Val): Reduced mitochondrial antioxidant defense - supplement CoQ10, NAC",
      "ACTN3 CT: Mixed muscle fiber type - balanced training approach",
      "PPARGC1A CC: Superior aerobic capacity potential - capitalize with endurance training",
      "FOXO3 GT: Longevity heterozygote - supports healthy aging protocols",
      "COMT AG (Val/Met): Balanced dopamine metabolism - intermediate stress resilience",
      "HFE H63D carrier: Monitor ferritin levels periodically"
    ]
  },
  "microbiome": {
    "source": "Viome",
    "food_recs": {
      "source": "viome",
      "extractedAt": "2026-02-15T19:29:06Z",
      "pdfPath": "/Users/bsyrros/clawd/imports/health/labs/INBOX-d4ba496f-1355-499c-94c0-8f7f6899ba66.pdf",
      "ranks": {
        "superfood": [
          "Adzuki Beans",
          "Apple",
          "Bee Pollen",
          "Bone Broth (Fish)",
          "Bone Broth (Mammal)",
          "Capers",
          "Carp",
          "Cinnamon",
          "Cocoa (Unsweetened)",
          "Coffee",
          "Cranberry",
          "Dandelion Tea",
          "Ghee",
          "Ginger",
          "Grapefruit",
          "Grape Seed Oil",
          "Green Tea",
          "Herring",
          "Kiwi",
          "Lime",
          "Matcha",
          "Olive Oil",
          "Oregano",
          "Papaya",
          "Peppermint (Fresh)",
          "Pistachios",
          "Raspberry",
          "Rhubarb",
          "Soybeans (non-GMO)",
          "Spearmint (Fresh)",
          "Strawberry",
          "Tofu",
          "Turmeric",
          "Walnut Oil",
          "i",
          "Fruits & Grains",
          "Apricot",
          "Currant",
          "Kumquat",
          "Minimize",
          "Passionfruit",
          "Enjoy",
          "Proteins & Fat",
          "Cashew Milk",
          "Green Lentils",
          "Pumpkin Seeds",
          "Squid",
          "6 oz",
          "1 tsp",
          "Spices & Other",
          "Grape Leaves",
          "Superfood",
          "Herbal Tea",
          "White Tea"
        ],
        "enjoy": [
          "Minimize",
          "Blueberry",
          "Breadfruit",
          "Enjoy",
          "Fruits & Grains",
          "1/2 cup",
          "Superfood",
          "Millet",
          "Pear",
          "Pineapple",
          "Pomegranate",
          "Pummelo",
          "Raspberry",
          "Abalone",
          "Anchovies",
          "Black Beluga Lentils",
          "Blue Cheese",
          "Proteins & Fat",
          "Catfish",
          "Chestnuts",
          "Chicken (Dark Meat)",
          "Chickpeas",
          "(Unsweetened)",
          "Crayfish",
          "Eel",
          "Fava Beans",
          "Ghee",
          "Lobster",
          "Paneer",
          "Pea Protein Powder",
          "Salmon (Wild-Caught)",
          "Sesame Oil",
          "Turkey (White Meat)",
          "Yogurt (soy, plain)",
          "Allspice",
          "Apple Cider Vinegar",
          "Basil",
          "Bee Pollen",
          "Black Tea",
          "Spices & Other",
          "Kombucha",
          "Lavender Tea",
          "Maple Syrup",
          "Matcha",
          "Molasses",
          "Nettle Leaf Tea",
          "Nutritional Yeast",
          "Oregano",
          "Peppermint (Fresh)",
          "Tarragon",
          "Turmeric",
          "Vinegar (Unsweetened)",
          "2 tablespoons"
        ],
        "minimize": [
          "Superfood",
          "Bilberry",
          "Brown Rice",
          "Dragon Fruit",
          "Fruits & Grains",
          "Gooseberry",
          "Mangosteen",
          "Enjoy",
          "Orange",
          "Wild Rice",
          "1/2 cup, cooked",
          "Cod (Alaskan)",
          "Hazelnuts",
          "Proteins & Fat",
          "Kidney Beans",
          "Ostrich",
          "Peanuts",
          "Snapper",
          "Turbot",
          "Venison or Elk",
          "Yogurt (Cow Milk, Plain)",
          "Cane Sugar",
          "Spices & Other",
          "Coconut Water",
          "Horseradish",
          "Soy Sauce"
        ],
        "avoid": [
          "Barley",
          "Beef (Lean, Grass-Fed)",
          "Black Beans",
          "Buffalo",
          "Bulgur",
          "Caviar or Roe",
          "Couscous",
          "Crab (Pacific)",
          "Egg Yolk (Chicken or Duck)",
          "Goat",
          "Haddock",
          "Hemp Hearts",
          "Hemp Milk",
          "Hemp Protein Powder",
          "Kamut",
          "Lamb",
          "Pecans",
          "Pinto Beans",
          "Plum",
          "Pork (Lean)",
          "Shrimp (Domestic)",
          "Sprouted Rye Bread",
          "Sprouted Wheat Bread",
          "Triticale",
          "Trout (Cold Water)",
          "Watermelon"
        ]
      }
    },
    "scores": {},
    "last_sync": "2026-04-03T11:46:00.870275"
  },
  "vitals": {
    "blood_pressure": {
      "systolic": 138,
      "diastolic": 85,
      "pulse": 47,
      "date": "2026-03-24",
      "time": "08:24",
      "source": "InsideTracker/iHealth"
    },
    "weight": {
      "value_lbs": 234.0,
      "bmi": 30.9,
      "date": "2026-04-03 07:15:51",
      "source": "iHealth Nexus Pro"
    },
    "bp_history": [
      {
        "systolic": 173,
        "diastolic": 108,
        "pulse": 56,
        "date": "2026-02-17",
        "time": "06:59",
        "note": "",
        "source": "iHealth Export"
      },
      {
        "systolic": 166,
        "diastolic": 100,
        "pulse": 50,
        "date": "2026-02-17",
        "time": "07:01",
        "note": "",
        "source": "iHealth Export"
      },
      {
        "systolic": 165,
        "diastolic": 99,
        "pulse": 50,
        "date": "2026-02-17",
        "time": "07:03",
        "note": "",
        "source": "iHealth Export"
      },
      {
        "systolic": 159,
        "diastolic": 96,
        "pulse": 48,
        "date": "2026-02-17",
        "time": "07:05",
        "note": "",
        "source": "iHealth Export"
      },
      {
        "systolic": 148,
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